Name | 4-Acetyloxy-3-acetyloxymethyl-(N-benzyl-N-tertbutylamino)acetophenone hydrochloride |
Synonyms | 4-Acetyloxy-3-acetyloxymethyl-(N-benzyl-N-tertbutylamino)acetophenone hydrochloride |
CAS | 27475-27-0 |
Molecular Formula | C24H30ClNO5 |
Molar Mass | 447.96 |
Physical and Chemical Properties | Crystallization of chemical properties. |
Use | Use is an intermediate of salbutamol. |
p-hydroxyacetophenone can be chloromethylated with formaldehyde-hydrochloric acid to generate 3-(chloromethyl)-4-hydroxyacetophenone, and then esterified with acetic anhydride and acetic acid, and brominated with bromine To obtain 4-hydroxy-3-hydroxymethylα-bromoacetophenone diacetate, and then amination with N-benzyl tert-butylamine to prepare the product.